The Horizon 2020-funded project, SHERPA (Shaping the Ethical Dimensions of Smart Information Systems), analyses how Artificial Intelligence (AI) and big data analytics impact ethics and human rights. The project is developing novel ways to understand and address these challenges to find desirable and sustainable solutions that can benefit both innovators and society. More concretely, SHERPA will: 1) represent and visualise the ethical and human rights challenges of Smart Information Systems (SIS) through case studies, scenarios and artistic representations; 2) work with a range of stakeholders to identify their concerns and preferred solutions; 3) develop and publish a workbook on responsible development of SIS; 4) present technical and regulatory options; 5) validate and prioritise the proposals through multi-stakeholder focus groups; and 6) advocate, promote and implement the most promising solutions.